Pathogenes Inc.

Rio has signs of EPM.  He also has laminitis and other metabolic issues.  The depression and wobbly head indicate the organism is in his CNS.  The ataxia and weakness are prominent.  His Peptide ELISA support the diagnosis of EPM.

Rio is not depressed and his weakness and vestibular signs are much improved.  He responded quickly to Oroquin-10 although he had received other anti-protozoal therapy prior and during the Oroquin-10 treatment.  There are several videos below showing his progress.

There are subtle differences in the gait that move CVM (cervical vetebral malformation) above EPM on the differential list as a cause of ataxia in this horse.  Peptide ELISA and neck radiographs confired a diagnosis of CVM

There are subtle differences in the gait that move CVM (cervical vetebral malformation) above EPM on the differential list as a cause of ataxia in this horse.  Peptide ELISA and neck radiographs confired a diagnosis of CVM

This horse, Pilot, has severe, acute encephalomyelitis due to S. neurona organisms in the CNS.  The organism was isolated from the brain tissue.  This horse demonstrates a grade III neurological lameness/ataxia and has central nervous system disease including vestibular deficits.

This video shows the horse at three times during his crisis.  Initially you see him as he is recovering although still a grade III.  He is 110 days after infection.  The second section shows him at the initial treatment, at 80 days post infection and just after he experienced a seizure.  At the time of the seizure he had EPM for 80 days with mild signs of ataxia, grade I, and vestibluar lesions indicative of central CNS disease. In the last section he is shown a day after initial treatment. This horse progressed to a grade I with intensive treatment and is maintained as a pasture pet. 

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This mare had been diagnosed with relapsing EPM.  Results from the Peptide ELISA indicated neck films were appropriate.  A lesion was found on radiographs and a confirmed diagnosis of Wobbler Syndrome was made.

Rio is going up and down hills.  It will take careful hand walking up and down to regain his muscle strength.