top of page



Pathogenes mission is to develop molecular tools for the diagnosis and treatment of animal diseases.

Blogs
Search


sellison23
Jan 3
Good Lesson from 2024
Nyambe Pathogenes made good strides in our horse drug development and case analysis this year. Each case gives us insight into the...
198


sellison23
Sep 24, 2024
S. neurona may elicit the JAK/STAT pathway in disease
Tongue paresis following S. neurona infection Do you wonder why researchers often can't find Sarcocystis neurona in the tissues of a...
81


sellison23
Aug 16, 2024
Equine protozoal myeloencephalitis in 2002
As we burn 20 year old files, as is our custom, we incinerated the early challenge experiment raw data. The signed exam forms, the CBC...
181


sellison23
Oct 16, 2023
Putative mechanism of CRP’s relationship to polyneuritis equi assay results
I spoke with Dr. Stefan Rose John, Institute of Biochemistry in Kiel Germany, a few years ago. Work he published in 2012 explains the...
260


sellison23
Oct 10, 2023
Field Effectiveness Study for PNE
Our polyneuritis (PNE) field study was a multi-site historical controlled, GCP (VICH GL9) study conducted under field conditions to...
400


sellison23
Sep 4, 2023
S. neurona SAG 6 gets attention
In 2000 Dr. Ellison investigated various genotypes of Sarcocystis neurona and Sarcocystis falcatula that were used by investigators T....
122


sellison23
Mar 22, 2023
Cell danger response: EPM or PNE?
The cell danger response (CDR) is a universal response to environmental threat or injury. Once the CDR is triggered, healing can’t be...
339


sellison23
Mar 15, 2023
Identification of biomarkers to slow neurodegenerative diseases
Biomarkers for treating neurodegenerative diseases
149


sellison23
Jan 2, 2023
Pathogenes Newsletter January 2023
The polyneuritis equi (PNE) field study has almost reached enrollment, but we need a few more horses. If you know anyone with a horse...
182




sellison23
Jun 14, 2022
The difference between “EPM” testing formats
The difference between EPM testing formats is explained
1,331


sellison23
May 20, 2022
Predicting the severity of EPM is possible
Predicting the severity of EPM using early signs
759


sellison23
May 13, 2022
What is the difference between EPM, EMS, and PNE (polyneuritis)
A pictorial description of sarcocystis infections in horses
678


sellison23
May 9, 2022
Gathering Data on EPM and PNE (polyneuritis equi)
Here is a photograph of some of our research yearlings. This herd was vaccinated with recombinant SAG 1 vaccine and challenged with a...
314


sellison23
Apr 30, 2022
The MP2/MPP ELISA in the differential diagnosis of polyneuritis (PNE)
The first time I spoke with Linda Turcotte, in 2015, she told me the tale of her old horse, Bay State Nestle. I thought we could help,...
1,009


sellison23
Apr 24, 2022
Interpreting S. neurona antibody tests
Explain what antibody tests in EPM mean
615


sellison23
Apr 18, 2022
Can polyneuritis be diagnosed with NfL found in serum, plasma, or exosomes?
Neurofilament light may be measurable and stratify patients to level of disease
282


sellison23
Apr 13, 2022
Test twice, treat once The PNE (polyneuritis) plan
Neurofilament light is associated with polyneuritis equi, PNE
321


sellison23
Apr 12, 2022
Innate Biomarkers for EPM and PNE (polyneuritis)
CRP is a biomarker for EPM, EMS, and PNE
145


sellison23
Apr 11, 2022
At the bench at Pathogenes…acute phase EPM markers
Controlled infection challenge with S. neurona shows serum amyloid A is a late event after infection
73
bottom of page