Putative mechanism of CRP’s relationship to polyneuritis equi assay results
I spoke with Dr. Stefan Rose John, Institute of Biochemistry in Kiel Germany, a few years ago. Work he published in 2012 explains the...
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sellison23
- Oct 13
- 4 min
Endpoints in clinical trials have to be relevant
How do you know when something is meaningful or just a conincidence?Meaningful veterinary clinical trials that lead to drug licensing...
150
sellison23
- Oct 10
- 5 min
Field Effectiveness Study for PNE
Our polyneuritis (PNE) field study was a multi-site historical controlled, GCP (VICH GL9) study conducted under field conditions to...
193
sellison23
- Oct 9
- 3 min
Innate immune responses to S. neurona
The purpose of a research experiment is to answer a question or questions. One should design the experiement to remove as much ambiguity...
83
sellison23
- Sep 4
- 3 min
S. neurona SAG 6 gets attention
In 2000 Dr. Ellison investigated various genotypes of Sarcocystis neurona and Sarcocystis falcatula that were used by investigators T....
80
sellison23
- Mar 22
- 2 min
Cell danger response: EPM or PNE?
The cell danger response (CDR) is a universal response to environmental threat or injury. Once the CDR is triggered, healing can’t be...
211
sellison23
- Mar 15
- 3 min
Identification of biomarkers to slow neurodegenerative diseases
Biomarkers for treating neurodegenerative diseases
122
sellison23
- Feb 9
- 5 min
What does it take to bring drug to market? Can I give it away to patients?
The first step to bringing a drug to market is inventing a new drug. The invention is based on an original idea that is spurred by...
124
sellison23
- Jan 2
- 2 min
Pathogenes Newsletter January 2023
The polyneuritis equi (PNE) field study has almost reached enrollment, but we need a few more horses. If you know anyone with a horse...
114
sellison23
- Jun 14, 2022
- 9 min
The difference between “EPM” testing formats
The difference between EPM testing formats is explained
629
sellison23
- May 20, 2022
- 7 min
Predicting the severity of EPM is possible
Predicting the severity of EPM using early signs
435
sellison23
- May 13, 2022
- 0 min
What is the difference between EPM, EMS, and PNE (polyneuritis)
A pictorial description of sarcocystis infections in horses
428
sellison23
- May 9, 2022
- 6 min
Gathering Data on EPM and PNE (polyneuritis equi)
Here is a photograph of some of our research yearlings. This herd was vaccinated with recombinant SAG 1 vaccine and challenged with a...
209
sellison23
- Apr 30, 2022
- 6 min
The MP2/MPP ELISA in the differential diagnosis of polyneuritis (PNE)
The first time I spoke with Linda Turcotte, in 2015, she told me the tale of her old horse, Bay State Nestle. I thought we could help,...
579
sellison23
- Apr 24, 2022
- 8 min
Interpreting S. neurona antibody tests
Explain what antibody tests in EPM mean
327
sellison23
- Apr 18, 2022
- 5 min
Can PNE (polyneuritis) be diagnosed with NfL found in serum, plasma, or exosomes?
Neurofilament light may be measurable and stratify patients to level of disease
185
sellison23
- Apr 13, 2022
- 5 min
Test twice, treat once The PNE (polyneuritis) plan
Neurofilament light is associated with polyneuritis equi, PNE
170
sellison23
- Apr 12, 2022
- 5 min
Innate Biomarkers for EPM and PNE (polyneuritis)
CRP is a biomarker for EPM, EMS, and PNE
64
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